Mahesh Bikkina Selected Research

BB-10153

8/2006

Dose escalation trial of the efficacy, safety, and pharmacokinetics of a novel fibrinolytic agent, BB-10153, in patients with ST elevation MI: results of the TIMI 31 trial.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Mahesh Bikkina Research Topics

Disease

7	Thrombosis (Thrombus) 10/2019 - 08/2006
4	Hemorrhage 01/2023 - 08/2006
3	Cardiovascular Diseases (Cardiovascular Disease) 10/2019 - 06/2011
3	ST Elevation Myocardial Infarction 10/2019 - 08/2006
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2011 - 06/2009
2	Pathologic Constriction (Stenosis) 01/2023 - 10/2017
2	Aneurysm (Aneurysms) 01/2023 - 01/2010
2	Anaphylaxis (Anaphylactic Shock) 03/2021 - 08/2006
2	Atrial Fibrillation 08/2020 - 01/2015
2	Endocarditis 01/2020 - 01/2016
2	Myocardial Infarction 10/2019 - 12/2012
2	Chest Pain (Chest Pains) 01/2017 - 12/2012
2	Stroke (Strokes) 01/2015 - 08/2006
1	COVID-19 01/2021
1	Diabetes Mellitus 01/2021
1	Infections 01/2021
1	Acute Kidney Injury (Acute Renal Failure) 01/2021
1	Spasm (Spasms) 08/2020
1	Left Ventricular Dysfunction 01/2020
1	Cardiotoxicity 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Neoplasms (Cancer) 01/2019
1	Heart Block 12/2017
1	Hyperemia 10/2017
1	Hypoplastic Left Heart Syndrome 01/2017
1	Takotsubo Cardiomyopathy 07/2016
1	Torsades de Pointes (Torsade de Pointes) 05/2016
1	Bacteremia 01/2016
1	Atherosclerosis 01/2015
1	Thromboembolism 01/2015
1	Coronary Vasospasm (Coronary Artery Vasospasm) 01/2014
1	Subdural Hematoma (Subdural Hemorrhage) 01/2010
1	Hypertension (High Blood Pressure) 01/2010
1	Vascular Remodeling 01/2010
1	Coronary Aneurysm (Aneurysm, Coronary) 01/2010
1	Type 2 Diabetes Mellitus (MODY) 01/2010
1	Cardiogenic Shock 08/2006
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 08/2006

Drug/Important Bio-Agent (IBA)

2	omega-Chloroacetophenone (Mace)IBA 10/2019 - 11/2013
2	Clopidogrel (Plavix)FDA Link 11/2016 - 01/2010
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2016 - 01/2010
1	IodineIBA 03/2021
1	Coloring Agents (Dyes)IBA 03/2021
1	GadoliniumIBA 03/2021
1	Ferritins (Ferritin)IBA 01/2021
1	fibrin fragment D (D-dimer)IBA 01/2021
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2020
1	Penicillins (Penicillin)FDA Link 01/2020
1	bivalirudin (Angiomax)FDA Link 10/2019
1	Heparin (Liquaemin)FDA LinkGeneric 10/2019
1	AnthracyclinesIBA 01/2019
1	Trastuzumab (Herceptin)FDA Link 01/2019
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2019
1	Adenosine (Adenocard)FDA LinkGeneric 10/2017
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 07/2016
1	Serotonin (5 Hydroxytryptamine)IBA 07/2016
1	Clarithromycin (Biaxin)FDA LinkGeneric 05/2016
1	Dabigatran FDA Link 01/2015
1	AntithrombinsIBA 01/2015
1	Nitroglycerin (Dynamite)FDA LinkGeneric 01/2014
1	Amiodarone (Amiodarona)FDA LinkGeneric 09/2012
1	Phenobarbital (Luminal)FDA Link 01/2010
1	PolymersIBA 01/2010
1	Sirolimus (Rapamycin)FDA Link 01/2010
1	Troponin IIBA 10/2009
1	BB-10153IBA 08/2006
1	Thrombin FDA Link 08/2006
1	EnzymesIBA 08/2006
1	Plasminogen Activators (Plasminogen Activator)IBA 08/2006
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 08/2006

Therapy/Procedure

5	Stents 10/2019 - 06/2009
4	Therapeutics 03/2021 - 01/2010
4	Drug-Eluting Stents 01/2011 - 06/2009
3	Percutaneous Coronary Intervention 10/2019 - 01/2010
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 11/2016 - 01/2015
2	Length of Stay 12/2012 - 10/2009
1	Sutures (Suture) 01/2023
1	Blood Transfusion (Blood Transfusions) 01/2023
1	Artificial Respiration (Mechanical Ventilation) 01/2021
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2021
1	Catheter Ablation 08/2020
1	Radiofrequency Ablation 08/2020
1	Drug Therapy (Chemotherapy) 01/2019
1	Fontan Procedure (Fontan Operation) 01/2017
1	Renal Dialysis (Hemodialysis) 01/2016
1	Heart Transplantation (Grafting, Heart) 01/2015
1	Secondary Prevention 06/2011
1	Ligation 01/2010